Veröffentlichungen

Wissenschaftliche Arbeiten, die aus der interdisziplinären Forschungsgruppe Tinnitus seit 2003 hervorgegangen sind:

2011

Gleich O, Strutz J (2011) The Effect of Gabapentin on Gap Detection and Forward Masking in Young and Old Gerbils. Ear Hear. Jul 1. [Epub ahead of print]

Hall DA, Lainez MJ, Newman CW, Ganz Sanchez T, Egler M, Tennigkeit F, Koch M, Langguth B (2011) Treatment options for subjective tinnitus: Self reports from a sample of general practitioners and ENT physicians within Europe and the USA. BMC Health Serv Res. 2011 Nov 4;11(1):302.

Kleinjung T, Steffens T, Landgrebe M, Vielsmeier V, Frank E, Burger J, Strutz J, Hajak G, Langguth B (2011) Repetitive transcranial magnetic stimulation for tinnitus treatment: No enhancement by the dopamine and noradrenaline reuptake inhibitor bupropion. Brain Stimul. Apr;4(2):65-70.

Kreuzer PM, Landgrebe M, Schecklmann M, Poeppl TB, Vielsmeier V, Hajak G, Kleinjung T, Langguth B. (2011) Can Temporal Repetitive Transcranial Magnetic Stimulation be Enhanced by Targeting Affective Components of Tinnitus with Frontal rTMS? A Randomized Controlled Pilot Trial. Syst Neurosci. 2011;5:88. Epub 2011 Nov 4.

Langguth B, Elgoyhen AB. (2011) Emerging pharmacotherapy of tinnitus. Expert Opin Emerg Drugs. Dec 8. [Epub ahead of print]

Langguth B, Landgrebe M, Kleinjung T, Sand GP, Hajak G (2011) Tinnitus and depression. World J Biol Psychiatry. May 13. [Epub ahead of print]

Langguth B (2011) A review of tinnitus symptoms beyond 'ringing in the ears': a call to action. Curr Med Res Opin. Jun 23

Langguth B, Kleinjung T, Landgrebe M (2011) Tinnitus: The Complexity of Standardization. Eval Eval Health Prof. Jan 10

Schecklmann M, Landgrebe M, Poeppl TB, Kreuzer P, Männer P, Marienhagen J, Wack DS, Kleinjung, T, Hajak G, Langguth B. (2011) Neural correlates of tinnitus duration and Distress: A positron emission tomography study. Hum Brain Mapp. 2011 Oct 22. doi: 10.1002/hbm.21426.[Epub ahead of print]

Schlee W, Kleinjung T, Hiller W, Goebel G, Kolassa IT, Langguth B. (2011) Does tinnitus distress depend on age of onset? PLoS One. 2011;6(11):e27379. Epub 2011 Nov 18.

Vielsmeier V, Kleinjung T, Strutz J, Bürgers R, Kreuzer PM, Langguth B (2011) Tinnitus with Temporomandibular Joint Disorders: A Specific Entity of Tinnitus Patients? Otolaryngol Head Neck Surg. Jun 25

Zeman F, Koller M, Figueiredo R, Azevedo A, Rates M, Coelho C, Kleinjung T, De Ridder D, Langguth B, Landgrebe M (2011) Tinnitus Handicap Inventory for Evaluating Treatment Effects: Which Changes Are Clinically Relevant? Otolaryngol Head Neck Surg. Apr 4. [Epub ahead of print]

2010
Biesinger E, Kipman U, Schätz S, Langguth B (2010) Qigong for the treatment of tinnitus: A prospectiverandomized controlled study. J Psychosom Res. 2010 Sep;69(3):299-304

Elgoyhen AB, Langguth B (2010) Pharmacological approaches to the treatment of tinnitus. Drug Discov Today. 2010 Apr;15(7-8):300-5

Frank E, Landgrebe M, Kleinjung T, Hajak G, Langguth B (2010) Burst transcranial magnetic stimulation for the treatment of tinnitus. CNS Spectr. Aug;15(8):536-7

Frank G, Kleinjung T, Landgrebe M, Vielsmeier V, Steffenhagen C, Burger J, Frank E, Vollberg G, Hajak G, Langguth B (2010) Left temporal low-frequency rTMS for the treatment of tinnitus: clinical predictors of treatment outcome - a retrospective study. Eur J Neurol. Jul;17(7):951-6

Landgrebe M, Zeman F, Koller M, Eberl Y, Mohr M, Reiter J, Staudinger S, Hajak G, Langguth B (2010) The Tinnitus Research Initiative (TRI) database: A new approach for delineation of tinnitus subtypes and generation of predictors for treatment outcome. BMC Med Inform Decis Mak. Aug 3;10:42

Langguth B, Kleinjung T, Landgrebe M, de Ridder D, Hajak G (2010) rTMS for the treatment of tinnitus: the role of neuronavigation for coil positioning. Neurophysiol Clin. Mar;40(1):45-58

Langguth B, Landgrebe M, Wittmann M, Kleinjung T, Hajak G (2010) Persistent tinnitus induced by tricyclic antidepressants. J Psychopharmacol. Aug;24(8):1273-5

Lorenz I, Müller N, Schlee W, Langguth B, Weisz N (2010) Short-term Effects of Single rTMS Sessions on Auditory Evoked Activity in Chronic Tinnitus Patients. J Neurophysiol. Jun 30

Marcondes RA, Sanchez TG, Kii MA, Ono CR, Buchpiguel CA, Langguth B, Marcolin MA (2010) Repetitive transcranial magnetic stimulation improve tinnitus in normal hearing patients: a double-blind controlled, clinical and neuroimaging outcome study. Eur J Neurol. Jan;17(1):38-44

2009
Azevedo AA, Langguth B, de Oliveira PM, Figureido RR (2009) Tinnitus treatment with piribedil guided by electroencephalography and acoustic otoemissions. Otol Neurotol. Aug;30(5):676-80

Kleinjung T, Langguth B. (2009) Strategies for enhancement of transcranial magnetic stimulation effects in tinnitus patients. Int Tinnitus J. 15(2):154-60

Kleinjung T, Steffens T, Landgrebe N, Vielsmeier V, Frank E, Hajak G, Strutz J, Langguth B (2009) Levodopa does not enhance the effect of low-frequency repetitive transcranial magnetic stimulation in tinnitus treatment. Otolaryngol Head Neck Surg. 140:92-95

Kleinjung T, Steffens T, Strutz J, Langguth B (2009) Curing tinnitus with a Cochlear Implant in a patient with unilateral sudden deafness - a case report. Cases Journal

Landgrebe M, Langguth B, Rosengarth K, Braun S, Koch A, Kleinjung T, May A, de Ridder D, Hajak G (2009) Structural brain changes in tinnitus: Gray matter decrease in auditory and non-auditory brain areas. Neuroimage. May 15; 46(1):213-218

Landgrebe M, Frick U, Hauser S, Hajak G, Langguth B (2009) Association of tinnitus and electromagnetic hypersensitivity: Hints for a shared pathophysiology? PLoS One. 4(3)

Langguth B, Kleinjung T, Landgrebe M, de Ridder D, Hajak G, rTMS for the treatment of tinnitus: the role of neuronavigation for coil positioning. Neurophysiologie Clinique/Clinical Neurophysiology Volume 40, Issue 1, March 2010, Pages 45-58

Langguth B, Landgrebe M, Wittmann M, Kleinjung T, Hajak G. (2009) Persistent tinnitus induced by antidepressants. Journal of Psychopharmacology Oct 13

Langguth B, Salvi R, Elgoyhen AB. (2009) Emerging pharmacotherapy for tinnitus. Expert Opinion on Emerging Drugs. Dec;14(4):687-702

Marcondes RA, Sanchez TG, Ono CR, Buchpiguel CA, Marcolin MA, Langguth B. (2009) rTMS improbe tinnitus in normal hearing patients: a double-blind controlled, clinical and neuroimaging study. Eur J Neurol. 2009 Jul 9

Schlee W, Hartmann T, Langguth B, Weisz N (2009) Abnormal resting-state cortical coupling in chronic tinnitus. BMC Neurosci. Feb 19;10:11

2008
Vielsmeier V, Kleinjung T, Langguth B (2008) Transkranielle Magnetstimulation als neue Behandlungsoption des chronischen Tinnitus. Tinnitus-Forum 4-2008:22-24

Wilfurth SS, Landgrebe M, Kleinjung T, Hajak G, Langguth B (2008) Repetitive transkranielle Magnetstimulation (rTMS). Neue Therapieoption bei chronischem Tinnitus? Der Neurologe und Psychiater 11/08(9): 42-46

Landgrebe M, Nyuyki K, Frank E, Steffens T, Hauser S, Eichhammer P, Hajak G, Langguth B (2008) Effects of colour exposure on auditory and somatosensory perception - hints for cross-modal plasticity. Neuro Endocrinol Lett. 29(4): 518-521

Del Bo L, Forti S, Ambrosetti U, Serena C, Davide M, Gregorio U, Langguth B, Mancuso A (2008) Tinnitus aurium in persons with normal hearing: 55 years later. Otolaryngol Head Neck Surg 139(3):391-194

Langguth B, de Ridder D, Dornhoffer JL, Eichhammer P, Folmer RL, Frank E, Fregni F, Gerloff C, Khedr E, Kleinjung T, Landgrebe M, Lee S, Lefaucheur J-P, Londero A, Marcondes R, Moller AR, Pascual-Leone A, Plewnia C, Rossi S, Sanchez T, Sand P, Schlee W ,Steffens T, van de Heyning P, Hajak G (2008) Does rTMS/tDCS show efficacy in treating tinnitus patients? Brain stimulation 1(3):192-205

Langguth B, Landgrebe M, Hajak G, Kleinjung T (2008) In reference to: Maintenance Repetitive Transcranial Magnetic Stimulation Can Inhibit The Return of Tinnitus. Laryngoscope118(12):2264

Langguth B, Landgrebe M, Hajak G, Eichhammer P, de Ridder D, Kleinjung T (in press) Tinnitus and Transcranial Magnetic Stimulation. Seminars in Hearing

Landgrebe M, Barta W, Rosengarth K, Frick U, Hauser S, Langguth B, Rutschmann R, Greenlee MW, Hajak G, Eichhammer P (in press) Neuronal correlates of symptom formation in functional somatic syndromes: a fMRI study. Neuroimage

Landgrebe M, Binder H, Koller M, Eberl Y, Kleinjung T, Eichhammer P, Graf E, Hajak G, Langguth B (2008) Design of a placebo-controlled, randomized study of the efficacy of repetitive transcranial magnetic stimulation for the treatment of chronic tinnitus. BMC Psychiatry 8:23

Langguth B, Landgrebe M, Hajak G, Eichhammer P, Vielsmeier V, Kleinjung T (2008) Transcranial Magnetic Stimulation: A new promising approach for the treatment of tinnitus. ENT News17(1) 32-34

Kleinjung T, Eichhammer P, Landgrebe M, Sand P, Hajak G, Steffens T, Strutz J, Langguth B (2008) Combined temporal and prefrontal TMS for tinnitus treatment – a pilot study. Otolaryngol Head Neck Surg. 138(4) 497-501

Figueiredo RR, Langguth B, Mello de Oliviera P, Azevedo AA (2008) Tinnitus treatment with memantine. Otolaryngol Head Neck Surg. 138(4) 492-496

Langguth B, Kleinjung T, Frank E, Landgrebe M, Sand P, Dvorakova J, Frick U, Eichhammer P, Hajak G (2008) High-frequency priming stimulation does not enhance the effect of low-frequency rTMS in the treatment of tinnitus. Exp Brain Res. 184(4):587-91

2007
Dvoráková J, Anders M, Paclt I, Raboch J, Holcát M, Rathová L, Langguth B (2007) Repetitive transcranial magnetic stimulation and chronic tinnitus. Cesk Slov Neurol N 70/103(4): 371-374

Crönlein T, Langguth B, Geisler P, Hajak G (2007) Tinnitus and Insomnia. Progress in Brain Research 166:227-33

Eichhammer P, Hajak G, Kleinjung T, Landgrebe L, Langguth B (2007) TMS for treatment of chronic tinnitus – neurobiological effects. Progress in Brain Research 166:369-75

Eichhammer P, Hajak G, Kleinjung T, Landgrebe M, Langguth B (2007) Functional imaging of chronic tinnitus: the use of positron emission tomography. Progress in Brain Research 166:83-88

Kleinjung T, Fischer B, Langguth B, Sand PG, Hajak G, Dvorakova J, Eichhammer P (2007) Validation of the German-Version Tinnitus Handicap Inventory (THI) Psychiatr Prax 34(1 Suppl): 13-14

Kleinjung T, Steffens T, Sand P, Murthum T, Hajak G, Strutz J, Langguth B, Eichhammer P (2007) Which tinnitus patients benefit from transcranial magnetic stimulation? Otolaryngol Head Neck Surg. 137(4):589-95

Kleinjung T, Eichhammer P, Langguth B (2007) Transkranielle Magnetstimulation zur Behandlung von chronischem Tinnitus?. Z Audiol. 46(1):22-26

Kleinjung T, Steffens T, Londero A, Langguth B, (2007) Transcranial magnetic stimulation (TMS) for treatment of chronic tinnitus – clinical effects. Progress in Brain Research 166:359-551

Langguth B, Goodey R et al. (2007) Consensus for Tinnitus Patient Assessment and Treatment Outcome Measurement. Progress in Brain Research 166:525-536

Langguth B, Eichhammer P, Hajak G, Kleinjung T, Sand PG (2007) Tinnitus severity, depression and the Big Five personality traits. Progress in Brain Research 166: 221-226

Langguth B, Kleinjung T, Marienhagen J, Binder H, Sand PG, Hajak G, Eichhammer P (2007) Transcranial Magnetic Stimulation for the treatment of tinnitus: Effects on cortical excitability. BMC Neuroscience 2;8:45

Langguth B, Stadtlaender H, Landgrebe M, Elgoyhen AB, Coors H, Vielmeier V, Kleinjung T (2007) Tinnitus and Coxsackie B infectuions: a case series. Neuroendocrinology Letters 28(5)

May A, Hajak G, Gänßbauer S, Langguth B, Kleinjung T, Eichhammer P. (2007) Structural brain alterations following 5 days of intervention: Dynamic aspects of neuroplasticity. Cerebral Cortex 17:205-210

Sand PG, Langguth B, Kleinjung T, Eichhammer P (2007) Genetics of chronic tinnitus. Progress in Brain Research 166:159-68

Buch:
Langguth B, Hajak G, Kleinjung T, Cacace AT, Moller AR (2007) Tinnitus: Pathophysiology and Treatment: Progress in Brain Research, Volume 166; Elsevier, Amsterdam

2006
Kleinjung T, Steffens T, Strutz J, Eichhammer P, Hajak G, Langguth B (2006) [Transcranial magnetic stimulation for the treatment of tinnitus.] HNO. 54(9):665-666

Kleinjung T, Steffens T, Langguth B, Eichhammer P, Marienhagen J, Hajak G, Strutz J (2006) [Treatment of chronic tinnitus with neuronavigated repetitive Transcranial Magnetic Stimulation (rTMS).] HNO 54: 439-444

Kleinjung T, Langguth B, Fischer B, Hajak G, Eichhammer P, Sand PG (2006) Systematic Screening of the Serotonin Receptor 1A (5-HT1A) Gene in Chronic Tinnitus. J Otology 1: 65-128

Langguth B, Eichhammer P, Kreutzer A, Maenner A, Marienhagen J, Kleinjung T, Hajak G (2006) The impact of auditory cortex activity on characterizing and treating patients with chronic tinnitus - first results from a PET study. Acta Otolaryngologica Suppl 556:84-8.

Langguth B, Landgrebe M, Sand PG, Kleinjung T, Hajak G, Eichhammer P (2006) Niedrigfrequente repetitive transkranielle Magnetstimulation: Ein neues Therapieverfahren zur Behandlung des chronischen Tinnitus? Nervenheilkunde 25: 649-652

Langguth B, Zowe M, Landgrebe M, Sand P, Kleinjung T, Binder H, Hajak G, Eichhammer P (2006) Transcranial Magnetic Stimulation for the treatment of tinnitus: A new coil positioning method and first results. Brain Topography 18(4): 241-7

Langguth B, Eichhammer P, Kleinjung T, Pridmore S, Hajak G (2006) Repetitive Transcranial Magnetic Stimulation and chronic tinnitus. Acta Otolaryngologica Suppl 556:102-4

Londero A, Langguth B, De Ridder D, Bonfils P, Lefaucheur JP (2006) Repetitive transcranial magnetic stimulation (rTMS) : a new therapeutic approach in subjective tinnitus ? Neurophysiologie Clinique 36: 145-155

Pridmore S, Kleinjung T, Langguth B, Eichhammer P (2006) Transcranial magnetic stimulation (TMS), a potential treatment for tinnitus? Psychiatry and Clinical Neurosciences 60(2): 133-138

2005
Kleinjung T, Eichhammer P, Langguth B, Jacob P, Marienhagen J, Hajak G, Wolf SR, Strutz J (2005) Long-term effects of repetitive Transcranial Magnetic Stimulation (rTMS) in chronic tinnitus. Otolaryngol Head Neck Surg. 2005 132(4):566-9

Langguth B, Eichhammer P, Zowe M, Kleinjung T, Jacob P, Binder H, Sand P, Hajak G (2005) Altered motor cortex excitability in tinnitus patients: a hint at crossmodal plasticity. Neuroscience Letters 380:326-329

Langguth B, Eichhammer P, Marienhagen J, Kleinjung T, Sand P, Hajak G (2005) Low frequency repetitive transcranial magnetic stimulation (rTMS) in brain hyperexcitability disorders like tinnitus and auditory hallucinations. In: Plasticity and Signal Representation in the Auditory System. editors.: Syka J, Merzenich MM Springer: 285-290

2004
Eichhammer P, Langguth B, Zowe M, Kleinjung T, Jacob P, Sand P, Hajak G (2004) GABA-B-Associated Neuropsychiatric Disorders. Psychiatr. Praxis Suppl 1:44-46

Eichhammer P, Langguth B, Hajak G (2004) Comment on “Neuronavigated Repetitive Transcranial Magnetic Stimulation in Patients with Tinnitus: a short case series” Reply. Biol Psychiatry; 55(11): 1117-1118

Langguth B, Eichhammer P, Zowe M, Marienhagen J, Jacob P, Sand P, Hajak G (2004) Low Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) for the Treatment of Chronic Tinnitus - Are there Long-Term Effects? Psychiatrische Praxis Suppl 1:52-54

2003
Eichhammer P, Langguth B, Marienhagen J, Kleinjung T, Hajak G (2003) Neuronavigated repetitive transcranial magnetic stimulation in patients with tinnitus: a short case series. Biol Psychiatry 54:862-5

Langguth B, Eichhammer P, Wiegand R, Marienhegen J, Maenner P, Jacob P, Hajak G (2003) Neuronavigated rTMS in a patient with chronic tinnitus. Effects of 4 weeks treatment. Neuroreport 14:977-80